Comparative study of the levels of some biochemical and immunological variables between patients with polycystic ovarian syndrome with and without insulin resistance
DOI:
https://doi.org/10.5281/zenodo.10213908Keywords:
Adiponectin, Endophilin A2, Polycystic ovary syndrome, ResistinAbstract
This study aimed to determine the changes occurring in some immune variables in women suffering from polycystic ovary syndrome in Tikrit city to study the effect of this elevation on the emergence and development of the disease. These variables included ( Adeponectin, resistin, Beta klotho, Endophilin A2). The study included non-infected women as control group, women having polycystic ovarian syndrome who do not have insulin resistant, as well as those who have the disease but are insulin resistant. All the methodology of the immunological variables was done by ELIZA technic according to the instructor of the company leaflet.
According to the findings, there were no significant changes (p<0.05), in adiponectin level between the control group and the polycystic ovarian group with and without insulin resistant. the results indicated significant increasing in the level of Resistin in blood serum of the patients group (group 2 and grpup3) compared with the control group, there were no significant differences in the level of Beta Klotho and Endophilin A2 mean in blood serum between the control group and the other groups of patients (p<0.05). Its concluded from this study the most variable can be affected by polysysticovarian syndrome dieses is the resistin which increase in the patients groups Resistin plays an important role in polycystic ovary syndrome (PCOS) due to its association with insulin resistance in women with polycystic ovary syndrome, resistin is associated with androgens, especially testosterone, Therefore, polycystic ovarian syndrome increases both.
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